Not the normal one, but the long held myth that Komodo Dragons can kill with a bite because their mouths are so filthy that infection quickly sets in. Turns out the bite is deadly because its well, venomous.
So a ten foot, poisonous lizard that isn't too fussy about what it eats. Why is this thing not in more monster manuals? Still, there is no reason to let a little science mess with your fantasy. I can think of a lot of monsters that the 'dangerously filthy mouth' myth could add a level of fear to dungeon delvers.
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